What is a common complication in pregnancies complicated by Marfan syndrome?

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Aortic dissection is particularly relevant in pregnancies complicated by Marfan syndrome due to the connective tissue abnormalities inherent in this genetic condition. Women with Marfan syndrome have a predisposition to cardiovascular complications, including dilatation and rupture of the aorta. During pregnancy, the hemodynamic changes and increased blood volume can place additional stress on the aorta and other vessels, increasing the risk of dissection.

This risk is heightened during labor and delivery, where the stresses of contractions and increased circulatory demands can lead to serious consequences. Monitoring and intervention strategies are critical for these patients to mitigate potential cardiovascular complications as a result of the dynamic physiological changes occurring throughout pregnancy.

While preeclampsia, gestational hypertension, and gallbladder disease can occur during pregnancy, they are not specifically linked to the connective tissue abnormalities of Marfan syndrome to the extent that aortic dissection is. Thus, understanding the unique vulnerabilities present in this population is essential for effective patient care and management.

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